Tuesday, November 11, 2008

R.I.P. Marijuana Receptor Weight Loss Drugs

Not sure if you've heard of them since they never really hit North American shores.

They were a class of drugs that worked on the endocannabinoid receptors and multiple drugs companies were working on obesity drugs based on blocking CB-1 receptors and in so doing, decrease caloric intake.

The drugs were actually fairly effective, one of them had even been released, but unfortunately there was an unacceptably high incidence of adverse psychiatric affects including suicidal ideation and less than 2 years after their much bally-hoo'ed launch, they've been permanently pulled from the market and the drug companies have all quashed their development.

Could someone please invent a safe and efficacious medication for weight management?


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