Thursday, November 11, 2021

2021's Dumbest Scientifically Published Exercise Recommendation For The Treatment Of Obesity

[First written blog post since March 2020. What an awful 20 months. Though the pandemic is certainly not over yet, it feels like it's time to start writing again. Not sure what the frequency of posts will be, but it's nice to be back]
I wouldn't have believed it was real if I hadn't seen this phenomenon so many times before - a research study trying to tie their findings to the treatment of obesity despite the findings being either incapable of leading to clinically meaningful weight loss, or ridiculous to suggest in the first place. Here we've got both.
Published in Cell Reports Medicine, the paper Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men looked at the brown fat stores of Scandinavian men who alternate brief outdoor winter swims with a dash to the sauna 2-3x weekly. 
What'd they find?
The non-randomly selected winter swimmers, all 8 of them, whose average BMIs were 23.7 and whose average age was 25, were found, when exposed to cold, to generate more heat from their brown adipose tissue than their 8 age and weight matched controls. 
How many calories did that brown adipose tissue heat generation burn? If we take their results at face value (their results are orders of magnitude higher than found in a prior study of albeit older subjects), they report that during a "cooling period" of 30 minutes (there was no difference during a "comfort state"), resting energy expenditure was higher in the winter swimmers by an extrapolated 484kcal/24hours. They also reported that winter swimmers spent on average 11 weekly minutes in cold water. So during those 11 minutes the winter swimmers might well be burning 3.7 more calories than their non-winter swimming counterparts - the equivalent number you'd consume eating 1/10th of a carrot. 
The paper is full of various hypotheses to try to tease out the findings from this very small study. 
But what struck me was their final conclusion, 
"Finally, our findings motivate investigations of winter swimming as a lifestyle intervention for increased energy expenditure in obese subjects as a potential weight loss strategy."
Really? Your n=8, non-randomized, observational study of young men without obesity, that didn't control for any weight related variables, which showed that during their 11 minutes of winter-swimming the swimmers might burn 3.7 more calories per week for 4 months than non swimmers motivates investigations of winter swimming as a potential weight loss strategy in people with obesity?
Photo By Jaan Künnap - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=87539864


Saturday, November 06, 2021

Saturday Stories: Hygiene Theatre, The Lost Plot, Caving To Antivaxxers, And a Brief Announcement From Me

Justin Ling, in Macleans, on the persistence of hygiene theatre
Sarah Zhang, in The Atlantic, on how we've lost the plot on COVID.
Announcement wise - well I think it's time for me to start blogging again. Though COVID is definitely not gone, with vaccinations coming for our children, I feel more comfortable amplifying topics not-COVID related. Look for first post back this week highlighting the stupidest appeal to obesity in a journal article that I've ever seen. Also, it's that time of year again, and should any of you want to donate to my Movember fundraising, here's the link


Saturday, October 09, 2021

Saturday Stories: Kareem Abdul-Jabbar Edition


Kareem Abdul-Jabbar on his own substack Kareem.Substack.com with two stories about vaccination and the NBA.




Saturday, August 28, 2021

Saturday, August 21, 2021

Saturday Stories: Masks And Children, Protecting Unvaccinated Kids, And What's Safe To Do?


Judith Danovitch, in The New York Times, on how masks might help your children to learn.

Lael M. Yonker and Anthony J. Fischer, in Time, on how we can protect unvaccinated kids.

Helen Branswell, in STAT, polled some epidemiologists about what they were and were not comfortable doing this summer.


Saturday, July 31, 2021

Saturday, July 17, 2021

Saturday, July 10, 2021

Saturday, July 03, 2021

Saturday Stories: Base Rate Bias, Weight Bias, And The Future of Ventilation


Katelyn Jetelina, in Your Local Epidemiologist, explains base rate bias by way of Israel, Delta, and 50% of cases being found in those already vaccinated. 

Diana Duong, in the CMAJ, briefly interviews me regarding obesity, weight bias, and COVID.

Lidia Morawska, Joseph Allen, William Bahnfleth, Philomena M. Bluyssen, Atze Boerstra, Giorgio Buonanno, Junji Cao, Stephanie J. Dancer, Andres Floto, Francesco Franchimon, Trisha Greenhalgh, Charles Haworth, Jaap Hogeling, Christina Isaxon, Jose L. Jimenez, Jarek Kurnitski, Yuguo Li, Marcel Loomans, Guy Marks, Linsey C. Marr, Livio Mazzarella, Arsen Krikor Melikov, Shelly Miller, Donald K. Milton, William Nazaroff, Peter V. Nielsen, Catherine Noakes, Jordan Peccia, Kim Prather, Xavier Querol, Chandra Sekhar, Olli Seppänen, Shin-ichi Tanabe, Julian W. Tang, Raymond Tellier, Kwok Wai Tham, Pawel Wargocki, Aneta Wierzbicka, Maosheng Yao, in Science, on the paradigm shift needed to combat airborne respiratory infections.



Saturday, June 26, 2021

Saturday Stories: Vaccinating Kids, Ivermectin, and Novavax


Edward Nirenberg, Daniel A. Freedman, Risa Hoshino, Jonathan Howard, and Alastair McAlpine,  in BMJ Blogs, on vaccinating kids vs. COVID. 

Anna Merlan, in Vice, on the invermectin conspiracy mongers

Hilda Bastien, in The Atlantic, on why Novavax might be the best vaccine we've got. 



Saturday, June 19, 2021

Saturday Stories: Delta, Ventilation, and Childhood COVID

Jennifer Yang and Kenyon Wallace, in The Toronto Star, on how cities, provinces and countries awash in vaccines can still mess things up if they're not cautious with the Delta variant. 

Tavia Grant, in The Globe and Mail, on the need to address ventilation in workplaces.

Edward Nirenberg and Risa Hoshino, in Medpage Today, on COVID in childhood.


Saturday, June 05, 2021

Saturday Stories: The Finish Line and Microchips


Jessica Smith-Cross, in QP Briefing, on Ontario's (and really everywhere's) COVID finish line

James Heathers, in The Atlantic, ponders whether or not he received a microchip in his COVID vaccine.


Saturday, May 22, 2021

Saturday Stories: They Were Loved


More than 25,000 Canadians have been lost to COVID-19 (and terrible governance given the bulk of those deaths were preventable), Macleans is collecting their stories. Please take the time today to click at least a few.



Saturday, May 15, 2021

Saturday Stories: Vaccinating Kids, Hatred And COVID


Gideon M-K, in Medium, on whether or not we should be vaccinating kids against the coronavirus (tl;dr - yes) 

Bernie Farber and David Fisman, in The Globe and Mail, on the overlap between racism, hate, and COVID denialists. 

Photo byAnthony Crider; cropped by Beyond My Ken (talk) 20:37, 9 April 2018 (UTC) - Charlottesville "Unite the Right" Rally, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=68193094


Saturday, May 08, 2021

Saturday Stories: Blood Clots, NNTs, And Incentives


Kai Kupferschmidt and Gretchen Vogel, in Science, explore the future of vaccines with rare risks of blood clots.

Andrew Althouse, in Medscape, on vaccines and the failure of NNTs.

John Michael McGrath, in TVO, makes the case for paying people to get vaccinated



Saturday, April 17, 2021

Saturday, April 10, 2021

Saturday, March 27, 2021

Saturday, March 13, 2021

Saturday Stories: Vaccines For Longhaulers, EMT Reflections, And Societal Reopening


Akiko Iwasaki, in Medium, on how vaccination might help COVID longhaulers.

Jennifer Murphy, in The New York Times, reflects on her experiences as a NYC EMT during the worst of their pandemic.

Jane Philpott and David Walker, in The Ottawa Citizen, discuss the equitable reopening of society.


Saturday, March 06, 2021

Saturday, February 20, 2021

Saturday Stories: Which Vaccine Should You Get, And Summertime


Gideon Meyerowitz-Katz, in The Guardian, discusses which vaccine you should get.

James Hamblin, in The Atlantic, on what summer might look like (in the US mind you, here in Canada, given our exceedingly slow pace of vaccination, this might not apply)



Saturday, February 13, 2021

Saturday Stories: No Herd Immunity Without Vaccines, Hygiene Theatre, And Sleepwalking Into Disaster


Michaeleen Doucleff, in NPR, explains how a small town in Brazil has tragically shown us that without vaccines, herd immunity is impossible.

Derek Thompson, in The Atlantic, on the waste of resources and the disinformation that is hygiene theatre

Brooks Fallis, in The Globe and Mail, on how Canada is sleepwalking into our next disastrous surge.

Photo by By Jesus Solana from Madrid, Spain - Black sheep . Do u also feel different? // la Oveja negra. Tambien te sientes diferente?, CC BY 2.0 https://commons.wikimedia.org/w/index.php?curid=5050231



Saturday, January 30, 2021

Saturday Stories: Vaccines Alone Aren't Enough, Women And Vaccines, Why Every Country Should Be Aiming At #COVIDZero, J&J And Novavax


Angela Rasmussen, in Slate, on how we can't rely on vaccines alone to end this pandemic (this is especially true right now in Canada where our vaccination program is barely off the ground)

Alice Lu-Culligan and Akiko Iwasaki, in the New York Times, on the safety of COVID vaccines for women of all ages

Michael Baker and Martin McKee, in The Guardian, on the 16 reasons why every country should be aiming for #COVIDZero.

Derek Lowe, in Science and Translational Medicine, on the new vaccines on the block - Novavax and J&J


Saturday, January 09, 2021

Saturday, December 05, 2020