Tuesday, February 13, 2007

Underwear Makers Rejoice!

And rejoice too if you're sick of Food Guide posts because this isn't one of them!

Alli, a half-strength version of the prescription drug Xenical (Orlistat) has been approved for over the counter sales in the US and will become the first over the counter weight loss drug approved by the FDA.

The way Xenical works is pretty straightforward.

In the gut there are enzymes that help the body break down and absorb fat. One of these enzymes is called, "GI Lipase" and what Xenical does is block it from acting.

Consequently roughly 30% of the fat you might consume will be left unabsorbed and able to pass freely from your body.

And I do mean freely.

Side effects of Xenical may well include increase flatulence, oily stools, diarrhea and um, accidents.

Here's the discussion on side effects from Xenical's official website,

"These changes may include gas with oily discharge, an increased number of bowel movements, an urgent need to have them, and an inability to control them, particularly after meals containing higher amounts of fat than are recommended."
Folks who look to Alli to help them with their weight loss woes but don't also change their lifestyles will be in for a staining disappointment - best case scenario without a lifestyle change behind you, I imagine Alli will lead to a 3-6% weight loss.

The other issue of course is compliance. If you knew you were having a fatty meal (let's say you order in a pizza) - are you going to take a pill that will cause increased flatulence, painful diarrhea and um, accidents?

Lastly, if you think my picture's in poor taste, it's actually not what you might think.

Thanks to the crack research teams over at bookofjoeI bring you the underwear safe.... no burglar's going to look in there

(I'm not making this stuff up - if you want to buy it, click this link).